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Tenofovir diphosphate concentrations and prophylactic effect in a macaque model of rectal simian HIV transmission
OBJECTIVES: This study evaluated the relationship between intracellular tenofovir diphosphate concentrations in peripheral blood mononuclear cells and prophylactic efficacy in a macaque model for HIV pre-exposure prophylaxis (PrEP). METHODS: Macaques were challenged with simian HIV (SHIV) via rectal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130383/ https://ncbi.nlm.nih.gov/pubmed/24862094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku162 |
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