Tenofovir diphosphate concentrations and prophylactic effect in a macaque model of rectal simian HIV transmission

OBJECTIVES: This study evaluated the relationship between intracellular tenofovir diphosphate concentrations in peripheral blood mononuclear cells and prophylactic efficacy in a macaque model for HIV pre-exposure prophylaxis (PrEP). METHODS: Macaques were challenged with simian HIV (SHIV) via rectal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Anderson, Peter L., Glidden, David V., Bushman, Lane R., Heneine, Walid, García-Lerma, J. Gerardo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130383/
https://ncbi.nlm.nih.gov/pubmed/24862094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku162
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