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Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir

Background. Rectal human immunodeficiency virus (HIV) transmission is an important driver of the HIV epidemic. Optimally formulated gels of antiretroviral drugs are under development for preventing rectally acquired HIV. We investigated in a macaque model the pharmacokinetics and efficacy of 3 recta...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Infect Dis
Main Authors: Dobard, Charles W., Taylor, Andrew, Sharma, Sunita, Anderson, Peter L., Bushman, Lane R., Chuong, Dinh, Pau, Chou-Pong, Hanson, Debra, Wang, Lin, Garcia-Lerma, J. Gerardo, McGowan, Ian, Rohan, Lisa, Heneine, Walid
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655858/
https://ncbi.nlm.nih.gov/pubmed/26071566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv334
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