Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir

Background. Rectal human immunodeficiency virus (HIV) transmission is an important driver of the HIV epidemic. Optimally formulated gels of antiretroviral drugs are under development for preventing rectally acquired HIV. We investigated in a macaque model the pharmacokinetics and efficacy of 3 recta...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Dobard, Charles W., Taylor, Andrew, Sharma, Sunita, Anderson, Peter L., Bushman, Lane R., Chuong, Dinh, Pau, Chou-Pong, Hanson, Debra, Wang, Lin, Garcia-Lerma, J. Gerardo, McGowan, Ian, Rohan, Lisa, Heneine, Walid
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655858/
https://ncbi.nlm.nih.gov/pubmed/26071566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv334
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