Efficacy of topical tenofovir against transmission of a tenofovir-resistant SHIV in macaques

BACKGROUND: Topically delivered tenofovir (TFV) from intravaginal rings, tablets, or gels is being evaluated for HIV prevention. We previously demonstrated that TFV delivered vaginally by gel protected macaques from vaginal infection with SHIV. Here we investigated efficacy of the TFV gel against va...

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Enregistré dans:
Détails bibliographiques
Publié dans:Retrovirology
Auteurs principaux: Dobard, Charles W, Sharma, Sunita, Cong, Mian-er, West, Rolieria, Makarova, Natalia, Holder, Angela, Pau, Chou-Pong, Hanson, Debra L., Novembre, Francis J, Garcia-Lerma, Jose Gerardo, Heneine, Walid
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528693/
https://ncbi.nlm.nih.gov/pubmed/26253002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0195-z
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