Efficacy of topical tenofovir against transmission of a tenofovir-resistant SHIV in macaques

BACKGROUND: Topically delivered tenofovir (TFV) from intravaginal rings, tablets, or gels is being evaluated for HIV prevention. We previously demonstrated that TFV delivered vaginally by gel protected macaques from vaginal infection with SHIV. Here we investigated efficacy of the TFV gel against va...

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Dades bibliogràfiques
Publicat a:Retrovirology
Autors principals: Dobard, Charles W, Sharma, Sunita, Cong, Mian-er, West, Rolieria, Makarova, Natalia, Holder, Angela, Pau, Chou-Pong, Hanson, Debra L., Novembre, Francis J, Garcia-Lerma, Jose Gerardo, Heneine, Walid
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528693/
https://ncbi.nlm.nih.gov/pubmed/26253002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0195-z
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