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A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene
Ron is a human receptor for the macrophage-stimulating protein (MSP). Exon 11 skipping of Ron pre-mRNA produces the RonΔ165 protein that has a deletion of a 49 amino acid region in the β-chain extracellular domain. RonΔ165 is constitutively active even in the absence of its ligand. Through stepwise...
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| Veröffentlicht in: | Oncol Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528306/ https://ncbi.nlm.nih.gov/pubmed/24189591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2835 |
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