SRSF2 promotes splicing and transcription of exon 11 included isoform in Ron proto-oncogene

The product of proto-oncogene Ron is a human receptor for the macrophage-stimulating protein (MSP). Upon activation, Ron is able to induce cell dissociation, migration and matrix invasion. Exon 11 skipping of Ron pre-mRNA produces Ron△165 protein that is constitutively active even in the absence of...

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Gepubliceerd in:Biochim Biophys Acta
Hoofdauteurs: Moon, Heegyum, Cho, Sunghee, Loh, Tiing Jen, Oh, Hyun Kyung, Jang, Ha Na, Zhou, Jianhua, Kwon, Young-Soo, Liao, D. Joshua, Jun, Youngsoo, Eom, Soohyun, Ghigna, Claudia, Biamonti, Giuseppe, Green, Michael R, Zheng, Xuexiu, Shen, Haihong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535357/
https://ncbi.nlm.nih.gov/pubmed/25220236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.09.003
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