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A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene

Ron is a human receptor for the macrophage-stimulating protein (MSP). Exon 11 skipping of Ron pre-mRNA produces the RonΔ165 protein that has a deletion of a 49 amino acid region in the β-chain extracellular domain. RonΔ165 is constitutively active even in the absence of its ligand. Through stepwise...

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Dettagli Bibliografici
Pubblicato in:Oncol Rep
Autori principali: MOON, HEEGYUM, CHO, SUNGHEE, LOH, TIING JEN, ZHOU, JIANHUA, GHIGNA, CLAUDIA, BIAMONTI, GIUSEPPE, GREEN, MICHAEL R., ZHENG, XUEXIU, SHEN, HAIHONG
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528306/
https://ncbi.nlm.nih.gov/pubmed/24189591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2835
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