hnRNP A1 contacts exon 5 to promote exon 6 inclusion of apoptotic Fas gene

Fas is a transmembrane cell surface protein recognized by Fas ligand (FasL). When FasL binds to Fas, the target cells undergo apoptosis. A soluble Fas molecule that lacks the transmembrane domain is produced from skipping of exon 6 encoding this region in alternative splicing procedure. The soluble...

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Détails bibliographiques
Publié dans:Apoptosis
Auteurs principaux: Oh, Hyun kyung, Lee, Eunkyung, Jang, Ha Na, Lee, Jaehoon, Moon, Heegyum, Sheng, Zhi, Jun, Youngsoo, Loh, Tiing Jen, Cho, Sunghee, Zhou, Jianhua, Green, Michael R., Zheng, Xuexiu, Shen, Haihong
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533901/
https://ncbi.nlm.nih.gov/pubmed/23430061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0824-8
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