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hnRNP A1 contacts exon 5 to promote exon 6 inclusion of apoptotic Fas gene
Fas is a transmembrane cell surface protein recognized by Fas ligand (FasL). When FasL binds to Fas, the target cells undergo apoptosis. A soluble Fas molecule that lacks the transmembrane domain is produced from skipping of exon 6 encoding this region in alternative splicing procedure. The soluble...
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| 出版年: | Apoptosis |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4533901/ https://ncbi.nlm.nih.gov/pubmed/23430061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0824-8 |
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