STRUCTURAL BASIS OF TRANSCRIPTION INHIBITION BY CBR HYDROXAMIDINES AND CBR PYRAZOLES

CBR hydroxamidines are small-molecule inhibitors of bacterial RNA polymerase (RNAP) discovered through high-throughput-screening of synthetic-compound libraries. CBR pyrazoles are structurally related RNAP inhibitors discovered through “scaffold hopping” from CBR hydroxamidines. CBR hydroxamidines a...

Full description

Saved in:

Bibliographic Details
Published in:	Structure
Main Authors:	Feng, Yu, Degen, David, Wang, Xinyue, Gigliotti, Matthew, Liu, Shuang, Zhang, Yu, Das, Deepankar, Michalchuk, Trevor, Ebright, Yon W., Talaue, Meliza, Connell, Nancy, Ebright, Richard H.
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4526357/ https://ncbi.nlm.nih.gov/pubmed/26190576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.06.009
Tags:	Add Tag No Tags, Be the first to tag this record!

STRUCTURAL BASIS OF TRANSCRIPTION INHIBITION BY CBR HYDROXAMIDINES AND CBR PYRAZOLES

Similar Items