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Structural basis of transcription activation

Class II transcription activators function by binding to a DNA site overlapping a core promoter and stimulating isomerization of an initial RNA polymerase (RNAP)-promoter closed complex into a catalytically competent RNAP-promoter open complex. Here we report a 4.4 Å crystal structure of an intact b...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Feng, Yu, Zhang, Yu, Ebright, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905602/
https://ncbi.nlm.nih.gov/pubmed/27284196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf4417
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