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4-Acetoxyphenol Prevents RPE Oxidative Stress–Induced Necrosis by Functioning as an NRF2 Stabilizer
PURPOSE: Oxidative stress has been suggested to be a major risk factor for the pathogenesis of AMD. Retinal pigment epithelial (RPE) cells are essential for maintaining the homeostasis of the retina, and RPE cell death and the resultant photoreceptor apoptosis have been observed in dry AMD, especial...
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| Publicado en: | Invest Ophthalmol Vis Sci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4525684/ https://ncbi.nlm.nih.gov/pubmed/26241392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16401 |
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