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Nrf2 signaling is Impaired in the Aging RPE given an Oxidative Insult
Age-related macular degeneration (AMD) represents the leading cause of blindness in the elderly, yet no definitive therapy exists for early, dry disease. Several lines of evidence have implicated oxidative stress-induced damage to the retinal pigment epithelium (RPE) in the pathogenesis of AMD, sugg...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946784/ https://ncbi.nlm.nih.gov/pubmed/24216314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.10.024 |
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