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Decreased Membrane Complement Regulators in the RPE Contributes to AMD
Dysregulated complement is thought to play a central role in AMD pathogenesis, but the specific mechanisms have yet to be determined. In maculas of AMD specimens, we found that the complement regulatory protein, CD59, was increased in regions of uninvolved retinal pigmented epithelium (RPE) of early...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836183/ https://ncbi.nlm.nih.gov/pubmed/23097248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4128 |
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