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Decreased Membrane Complement Regulators in the RPE Contributes to AMD

Dysregulated complement is thought to play a central role in AMD pathogenesis, but the specific mechanisms have yet to be determined. In maculas of AMD specimens, we found that the complement regulatory protein, CD59, was increased in regions of uninvolved retinal pigmented epithelium (RPE) of early...

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Hlavní autoři: Ebrahimi, Katayoon B., Fijalkowski, Natalia, Cano, Marisol, Handa, James T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836183/
https://ncbi.nlm.nih.gov/pubmed/23097248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4128
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