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Decreased Membrane Complement Regulators in the RPE Contributes to AMD

Dysregulated complement is thought to play a central role in AMD pathogenesis, but the specific mechanisms have yet to be determined. In maculas of AMD specimens, we found that the complement regulatory protein, CD59, was increased in regions of uninvolved retinal pigmented epithelium (RPE) of early...

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書誌詳細
主要な著者: Ebrahimi, Katayoon B., Fijalkowski, Natalia, Cano, Marisol, Handa, James T.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836183/
https://ncbi.nlm.nih.gov/pubmed/23097248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4128
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