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Oxidative Stress Induces Mitochondrial Dysfunction and a Protective Unfolded Protein Response in RPE cells

How cells degenerate from oxidative stress in aging-related disease is incompletely understood. The study’s intent was to identify key cytoprotective pathways activated by oxidative stress, and determine the extent of their protection. Using an unbiased strategy with microarray analysis, retinal pig...

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Detalhes bibliográficos
Main Authors: Cano, Marisol, Wang, Lei, Wan, Jun, Barnett, Bradley P., Ebrahimi, Katayoon, Qian, Jiang, Handa, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960355/
https://ncbi.nlm.nih.gov/pubmed/24434119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.01.004
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