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Oxidative Stress Induces Mitochondrial Dysfunction and a Protective Unfolded Protein Response in RPE cells

How cells degenerate from oxidative stress in aging-related disease is incompletely understood. The study’s intent was to identify key cytoprotective pathways activated by oxidative stress, and determine the extent of their protection. Using an unbiased strategy with microarray analysis, retinal pig...

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Autori principali: Cano, Marisol, Wang, Lei, Wan, Jun, Barnett, Bradley P., Ebrahimi, Katayoon, Qian, Jiang, Handa, James T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960355/
https://ncbi.nlm.nih.gov/pubmed/24434119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.01.004
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