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Oxidative Stress Induces Mitochondrial Dysfunction and a Protective Unfolded Protein Response in RPE cells

How cells degenerate from oxidative stress in aging-related disease is incompletely understood. The study’s intent was to identify key cytoprotective pathways activated by oxidative stress, and determine the extent of their protection. Using an unbiased strategy with microarray analysis, retinal pig...

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Bibliografske podrobnosti
Main Authors: Cano, Marisol, Wang, Lei, Wan, Jun, Barnett, Bradley P., Ebrahimi, Katayoon, Qian, Jiang, Handa, James T.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960355/
https://ncbi.nlm.nih.gov/pubmed/24434119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.01.004
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