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Oxidative stress response and Nrf2 signaling in aging

Increasing oxidative stress, a major characteristic of aging, has been implicated in variety of age-related pathologies. In aging, oxidant production from several sources is increased while antioxidant enzymes, the primary lines of defense, are decreased. Repair systems, including the proteasomal de...

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Bibliografiske detaljer
Udgivet i:Free Radic Biol Med
Main Authors: Zhang, Hongqiao, Davies, Kelvin J. A., Forman, Henry Jay
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628850/
https://ncbi.nlm.nih.gov/pubmed/26066302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.05.036
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