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TGFβ1 rapidly activates Src through a non-canonical redox signaling mechanism

Transforming growth factor-β1 (TGF-β) is involved in multiple cellular processes through Src activation. In the canonical pathway, Src activation is initiated by pTyr530 dephosphorylation followed by a conformational change allowing Tyr419 auto-phosphorylation. A non-canonical pathway in which oxida...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arch Biochem Biophys
Prif Awduron: Zhang, Hongqiao, Davies, Kelvin J. A., Forman, Henry Jay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339486/
https://ncbi.nlm.nih.gov/pubmed/25585026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.01.001
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