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TGFβ1 rapidly activates Src through a non-canonical redox signaling mechanism
Transforming growth factor-β1 (TGF-β) is involved in multiple cellular processes through Src activation. In the canonical pathway, Src activation is initiated by pTyr530 dephosphorylation followed by a conformational change allowing Tyr419 auto-phosphorylation. A non-canonical pathway in which oxida...
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| Udgivet i: | Arch Biochem Biophys |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339486/ https://ncbi.nlm.nih.gov/pubmed/25585026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.01.001 |
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