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4-Hydroxynonenal activates Src through a non-canonical pathway that involves EGFR/PTP1B
Src, a non-receptor protein tyrosine kinase involved in many biological processes, can be activated through both redox-dependent and independent mechanisms. 4-Hydroxy-2-nonenal (HNE) is a lipid peroxidation product that is increased in pathophysiological conditions associated with Src activation. Th...
Shranjeno v:
| izdano v: | Free Radic Biol Med |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684732/ https://ncbi.nlm.nih.gov/pubmed/26453921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.08.025 |
| Oznake: |
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