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Glutathione synthesis and its role in redox signaling
Glutathione (GSH) is the most abundant antioxidant and a major detoxification agent in cells. It is synthesized through two-enzyme reaction catalyzed by glutamate cysteine ligase and glutathione synthetase, and its level is well regulated in response to redox change. Accumulating evidence suggests t...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422610/ https://ncbi.nlm.nih.gov/pubmed/22504020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2012.03.017 |
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