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Does Bach1 & C-Myc Dependent Redox Dysregulation of Nrf2 & Adaptive Homeostasis Decrease Cancer Risk in Ageing?

The Keap1-Nrf2 signal transduction pathway plays a major role in oxidant and electrophile induction of adaptive homeostasis that transiently and reversibly increases cellular and organismal protection from stress. By expanding (and then contracting) the normal homeostatic range of expression of stre...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Davies, Kelvin J. A., Forman, Henry Jay
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588462/
https://ncbi.nlm.nih.gov/pubmed/30695691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.01.028
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