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Does Bach1 & C-Myc Dependent Redox Dysregulation of Nrf2 & Adaptive Homeostasis Decrease Cancer Risk in Ageing?

The Keap1-Nrf2 signal transduction pathway plays a major role in oxidant and electrophile induction of adaptive homeostasis that transiently and reversibly increases cellular and organismal protection from stress. By expanding (and then contracting) the normal homeostatic range of expression of stre...

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Bibliografische gegevens
Gepubliceerd in:Free Radic Biol Med
Hoofdauteurs: Davies, Kelvin J. A., Forman, Henry Jay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588462/
https://ncbi.nlm.nih.gov/pubmed/30695691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.01.028
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