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Nrf2-dependent Induction of Proteasome and Pa28αβ Regulator Are Required for Adaptation to Oxidative Stress

The ability to adapt to acute oxidative stress (e.g. H(2)O(2), peroxynitrite, menadione, and paraquat) through transient alterations in gene expression is an important component of cellular defense mechanisms. We show that such adaptation includes Nrf2-dependent increases in cellular capacity to deg...

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Detalhes bibliográficos
Main Authors: Pickering, Andrew M., Linder, Robert A., Zhang, Hongqiao, Forman, Henry J., Davies, Kelvin J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323025/
https://ncbi.nlm.nih.gov/pubmed/22308036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.277145
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