Nrf2-dependent Induction of Proteasome and Pa28αβ Regulator Are Required for Adaptation to Oxidative Stress

The ability to adapt to acute oxidative stress (e.g. H(2)O(2), peroxynitrite, menadione, and paraquat) through transient alterations in gene expression is an important component of cellular defense mechanisms. We show that such adaptation includes Nrf2-dependent increases in cellular capacity to deg...

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Autori principali: Pickering, Andrew M., Linder, Robert A., Zhang, Hongqiao, Forman, Henry J., Davies, Kelvin J. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323025/
https://ncbi.nlm.nih.gov/pubmed/22308036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.277145
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