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Oxidative stress response and Nrf2 signaling in aging

Increasing oxidative stress, a major characteristic of aging, has been implicated in variety of age-related pathologies. In aging, oxidant production from several sources is increased while antioxidant enzymes, the primary lines of defense, are decreased. Repair systems, including the proteasomal de...

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Vydáno v:Free Radic Biol Med
Hlavní autoři: Zhang, Hongqiao, Davies, Kelvin J. A., Forman, Henry Jay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628850/
https://ncbi.nlm.nih.gov/pubmed/26066302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.05.036
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