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RPE Necroptosis in Response to Oxidative Stress and in AMD

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly. The underlying mechanism of non-neovascular AMD (dry AMD), also named geographic atrophy (GA) remains unclear and the mechanism of retinal pigment epithelial (RPE) cell death in AMD is controversial...

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Bibliographic Details
Published in:Ageing Res Rev
Main Authors: Hanus, Jakub, Anderson, Chastain, Wang, Shusheng
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661094/
https://ncbi.nlm.nih.gov/pubmed/26369358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2015.09.002
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