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Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

Autophagic dysregulation has been suggested in a broad range of neurodegenerative diseases including age-related macular degeneration (AMD). To test whether the autophagy pathway plays a critical role to protect retinal pigmented epithelial (RPE) cells against oxidative stress, we exposed ARPE-19 an...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Mitter, Sayak K, Song, Chunjuan, Qi, Xiaoping, Mao, Haoyu, Rao, Haripriya, Akin, Debra, Lewin, Alfred, Grant, Maria, Dunn, William, Ding, Jindong, Bowes Rickman, Catherine, Boulton, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502658/
https://ncbi.nlm.nih.gov/pubmed/25484094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.36184
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