Gene therapy in animal models of autosomal dominant retinitis pigmentosa

Por Rossmiller, Brian, Mao, Haoyu, Lewin, Alfred S.
Publicado em 2012

Gene Augmentation for adRP Mutations in RHO

Por Lewin, Alfred S., Rossmiller, Brian, Mao, Haoyu
Publicado em 2014

Gene Delivery of Wild-Type Rhodopsin Rescues Retinal Function in an Autosomal Dominant Retinitis Pigmentosa Mouse Model

Por Mao, Haoyu, Gorbatyuk, Marina S., Hauswirth, William W., Lewin, Alfred S.
Publicado em 2012

Long-Term Rescue of Retinal Structure and Function by Rhodopsin RNA Replacement with a Single Adeno-Associated Viral Vector in P23H RHO Transgenic Mice

Por Mao, Haoyu, Gorbatyuk, Marina S., Rossmiller, Brian, Hauswirth, William W., Lewin, Alfred S.
Publicado em 2012

Pathological Consequences of Long-Term Mitochondrial Oxidative Stress in the Mouse Retinal Pigment Epithelium

Por Seo, Soo-jung, Krebs, Mark P., Mao, Haoyu, Jones, Kyle, Conners, Mandy, Lewin, Alfred S.
Publicado em 2012

AAV Delivery of Wild-Type Rhodopsin Preserves Retinal Function in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa

Por Mao, Haoyu, James, Thomas, Schwein, Alison, Shabashvili, Arseniy E., Hauswirth, William W., Gorbatyuk, Marina S., Lewin, Alfred S.
Publicado em 2011

Systemic Treatment with a 5HT1a Agonist Induces Anti-oxidant Protection and Preserves the Retina from Mitochondrial Oxidative Stress

Por Biswal, Manas R., Ahmed, Chulbul M., Ildefonso, Cristhian J., Han, Pingyang, Li, Hong, Jivanji, Hiral, Mao, Haoyu, Lewin, Alfred S.
Publicado no Exp Eye Res (2015)

Mitochondrial Oxidative Stress in the Retinal Pigment Epithelium Leads to Localized Retinal Degeneration

Por Mao, Haoyu, Seo, Soo Jung, Biswal, Manas R., Li, Hong, Conners, Mandy, Nandyala, Arathi, Jones, Kyle, Le, Yun-Zheng, Lewin, Alfred S.
Publicado em 2014

The 5HT(1a) Receptor Agonist 8-Oh DPAT Induces Protection from Lipofuscin Accumulation and Oxidative Stress in the Retinal Pigment Epithelium

Por Thampi, Prajitha, Rao, Haripriya Vittal, Mitter, Sayak K., Cai, Jun, Mao, Haoyu, Li, Hong, Seo, Soojung, Qi, Xiaoping, Lewin, Alfred S., Romano, Carl, Boulton, Michael E.
Publicado em 2012

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

Por Mitter, Sayak K, Song, Chunjuan, Qi, Xiaoping, Mao, Haoyu, Rao, Haripriya, Akin, Debra, Lewin, Alfred, Grant, Maria, Dunn, William, Ding, Jindong, Bowes Rickman, Catherine, Boulton, Michael
Publicado no Autophagy (2014)