Systemic Treatment with a 5HT1a Agonist Induces Anti-oxidant Protection and Preserves the Retina from Mitochondrial Oxidative Stress

Chronic oxidative stress contributes to age related diseases including age related macular degeneration (AMD). Earlier work showed that the 5-hydroxy-tryptophan 1a (5HT1a) receptor agonist 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) protects retinal pigment epithelium (RPE) cells from hydrog...

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Bibliografiset tiedot
Julkaisussa:Exp Eye Res
Päätekijät: Biswal, Manas R., Ahmed, Chulbul M., Ildefonso, Cristhian J., Han, Pingyang, Li, Hong, Jivanji, Hiral, Mao, Haoyu, Lewin, Alfred S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624518/
https://ncbi.nlm.nih.gov/pubmed/26315784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.07.022
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