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Systemic Treatment with a 5HT1a Agonist Induces Anti-oxidant Protection and Preserves the Retina from Mitochondrial Oxidative Stress
Chronic oxidative stress contributes to age related diseases including age related macular degeneration (AMD). Earlier work showed that the 5-hydroxy-tryptophan 1a (5HT1a) receptor agonist 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) protects retinal pigment epithelium (RPE) cells from hydrog...
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| Udgivet i: | Exp Eye Res |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624518/ https://ncbi.nlm.nih.gov/pubmed/26315784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.07.022 |
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