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Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD

PURPOSE: To investigate whether antioxidant gene therapy protects the structure and function of retina in a murine model of RPE atrophy, and to determine whether antioxidant gene therapy can prevent degeneration once it has begun. METHODS: We induced mitochondrial oxidative stress in RPE by conditio...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Biswal, Manas R., Han, Pingyang, Zhu, Ping, Wang, Zhaoyang, Li, Hong, Ildefonso, Cristhian J., Lewin, Alfred S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338629/
https://ncbi.nlm.nih.gov/pubmed/28241311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21272
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