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Gene Therapy With the Caspase Activation and Recruitment Domain Reduces the Ocular Inflammatory Response

Inflammation is a key component of chronic and acute diseases of the eye. Our goal is to test anti-inflammatory genes delivered by an adeno-associated virus (AAV) vector as potential treatments for retinal inflammation. We developed a secretable and cell penetrating form of the caspase activation an...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Ildefonso, Cristhian J, Jaime, Henrique, Biswal, Manas R, Boye, Shannon E, Li, Qiuhong, Hauswirth, William W, Lewin, Alfred S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427880/
https://ncbi.nlm.nih.gov/pubmed/25698151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.30
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