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Gene Augmentation for adRP Mutations in RHO

Mutations in the gene for rhodopsin, RHO, cause autosomal dominant retinitis pigmentosa, a disease characterized by death of rod photoreceptor cells. At the end stage, when most rods are gone, cones die too, taking central vision with them. One goal of gene therapy, therefore, is to preserve central...

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Detalhes bibliográficos
Main Authors: Lewin, Alfred S., Rossmiller, Brian, Mao, Haoyu
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143106/
https://ncbi.nlm.nih.gov/pubmed/25037104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a017400
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