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Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells
Mounting evidence implicates chronic oxidative stress as a critical driver of the aging process. Down syndrome (DS) is characterized by a complex phenotype, including early senescence. DS cells display increased levels of reactive oxygen species (ROS) and mitochondrial structural and metabolic dysfu...
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| 出版年: | Aging Cell |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156351/ https://ncbi.nlm.nih.gov/pubmed/30028071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12812 |
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