ets-2 Promotes the Activation of a Mitochondrial Death Pathway in Down's Syndrome Neurons

Down's syndrome (DS) is characterized by mental retardation and development of Alzheimer's disease (AD). Oxidative stress and mitochondrial dysfunction are both related to neurodegeneration in DS. Several genes in chromosome 21 have been linked to neuronal death, including the transcriptio...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Helguera, Pablo, Pelsman, Alejandra, Pigino, Gustavo, Wolvetang, Ernst, Head, Elizabeth, Busciglio, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726094/
https://ncbi.nlm.nih.gov/pubmed/15745955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5107-04.2005
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