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ets-2 Promotes the Activation of a Mitochondrial Death Pathway in Down's Syndrome Neurons

Down's syndrome (DS) is characterized by mental retardation and development of Alzheimer's disease (AD). Oxidative stress and mitochondrial dysfunction are both related to neurodegeneration in DS. Several genes in chromosome 21 have been linked to neuronal death, including the transcriptio...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Helguera, Pablo, Pelsman, Alejandra, Pigino, Gustavo, Wolvetang, Ernst, Head, Elizabeth, Busciglio, Jorge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726094/
https://ncbi.nlm.nih.gov/pubmed/15745955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5107-04.2005
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