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Adaptive Downregulation of Mitochondrial Function in Down Syndrome
Mitochondrial dysfunction and oxidative stress are common features of Down syndrome (DS). However, the underlying mechanisms are not known. We investigated the relationship between abnormal energy metabolism and oxidative stress with transcriptional and functional changes in DS cells. Impaired mitoc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580189/ https://ncbi.nlm.nih.gov/pubmed/23312288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.12.005 |
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