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Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation

Artificial metalloenzymes (ArMs) formed by incorporating synthetic metal catalysts into protein scaffolds have the potential to impart to chemical reactions selectivity that would be difficult to achieve using metal catalysts alone. In this work, we covalently link an alkyne-substituted dirhodium ca...

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Publicat a:Nat Commun
Autors principals: Srivastava, Poonam, Yang, Hao, Ellis-Guardiola, Ken, Lewis, Jared C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525152/
https://ncbi.nlm.nih.gov/pubmed/26206238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8789
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