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Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation

Artificial metalloenzymes (ArMs) formed by incorporating synthetic metal catalysts into protein scaffolds have the potential to impart to chemical reactions selectivity that would be difficult to achieve using metal catalysts alone. In this work, we covalently link an alkyne-substituted dirhodium ca...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Srivastava, Poonam, Yang, Hao, Ellis-Guardiola, Ken, Lewis, Jared C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525152/
https://ncbi.nlm.nih.gov/pubmed/26206238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8789
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