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A General Method for Artificial Metalloenzyme Formation via Strain-Promoted Azide-Alkyne Cycloaddition
Strain-promoted azide-alkyne cycloaddition (SPAAC) can be used to generate artificial metalloenzymes (ArMs) from scaffold proteins containing a p-azido-L-phenylalanine (Az) residue and catalytically active bicyclononyne-substituted metal complexes. The high efficiency of this reaction allows rapid A...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3996923/ https://ncbi.nlm.nih.gov/pubmed/24376040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300661 |
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