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Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation

Artificial metalloenzymes (ArMs) formed by incorporating synthetic metal catalysts into protein scaffolds have the potential to impart to chemical reactions selectivity that would be difficult to achieve using metal catalysts alone. In this work, we covalently link an alkyne-substituted dirhodium ca...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Srivastava, Poonam, Yang, Hao, Ellis-Guardiola, Ken, Lewis, Jared C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525152/
https://ncbi.nlm.nih.gov/pubmed/26206238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8789
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