Natural product (−)‐gossypol inhibits colon cancer cell growth by targeting RNA‐binding protein Musashi‐1

Musashi‐1 (MSI1) is an RNA‐binding protein that acts as a translation activator or repressor of target mRNAs. The best‐characterized MSI1 target is Numb mRNA, whose encoded protein negatively regulates Notch signaling. Additional MSI1 targets include the mRNAs for the tumor suppressor protein APC th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Lan, Lan, Appelman, Carl, Smith, Amber R., Yu, Jia, Larsen, Sarah, Marquez, Rebecca T., Liu, Hao, Wu, Xiaoqing, Gao, Philip, Roy, Anuradha, Anbanandam, Asokan, Gowthaman, Ragul, Karanicolas, John, De Guzman, Roberto N., Rogers, Steven, Aubé, Jeffrey, Ji, Min, Cohen, Robert S., Neufeld, Kristi L., Xu, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523432/
https://ncbi.nlm.nih.gov/pubmed/25933687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.03.014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados