Identification and Validation of an Aspergillus nidulans Secondary Metabolite Derivative as an Inhibitor of the Musashi-RNA Interaction

RNA-binding protein Musashi-1 (MSI1) is a key regulator of several stem cell populations. MSI1 is involved in tumor proliferation and maintenance, and it regulates target mRNAs at the translational level. The known mRNA targets of MSI1 include Numb, APC, and P21(WAF-1), key regulators of Notch/Wnt s...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autori: Lan, Lan, Liu, Jiajun, Xing, Minli, Smith, Amber R., Wang, Jinan, Wu, Xiaoqing, Appelman, Carl, Li, Ke, Roy, Anuradha, Gowthaman, Ragul, Karanicolas, John, Somoza, Amber D., Wang, Clay C. C., Miao, Yinglong, De Guzman, Roberto, Oakley, Berl R., Neufeld, Kristi L., Xu, Liang
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463734/
https://ncbi.nlm.nih.gov/pubmed/32784494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082221
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items