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Novel Double-negative Feedback Loop between Adenomatous Polyposis Coli and Musashi1 in Colon Epithelia

Loss of tumor suppressor adenomatous polyposis coli (APC) is thought to initiate the majority of all colorectal cancers. The predominant theory of colorectal carcinogenesis implicates stem cells as the initiating cells. However, relatively little is known about the function of APC in governing the h...

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Détails bibliographiques
Auteurs principaux: Spears, Erick, Neufeld, Kristi L.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037606/
https://ncbi.nlm.nih.gov/pubmed/21199875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.205922
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