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Novel Double-negative Feedback Loop between Adenomatous Polyposis Coli and Musashi1 in Colon Epithelia

Loss of tumor suppressor adenomatous polyposis coli (APC) is thought to initiate the majority of all colorectal cancers. The predominant theory of colorectal carcinogenesis implicates stem cells as the initiating cells. However, relatively little is known about the function of APC in governing the h...

詳細記述

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書誌詳細
主要な著者: Spears, Erick, Neufeld, Kristi L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037606/
https://ncbi.nlm.nih.gov/pubmed/21199875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.205922
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