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Novel Double-negative Feedback Loop between Adenomatous Polyposis Coli and Musashi1 in Colon Epithelia

Loss of tumor suppressor adenomatous polyposis coli (APC) is thought to initiate the majority of all colorectal cancers. The predominant theory of colorectal carcinogenesis implicates stem cells as the initiating cells. However, relatively little is known about the function of APC in governing the h...

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Detalhes bibliográficos
Main Authors: Spears, Erick, Neufeld, Kristi L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037606/
https://ncbi.nlm.nih.gov/pubmed/21199875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.205922
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