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Novel Double-negative Feedback Loop between Adenomatous Polyposis Coli and Musashi1 in Colon Epithelia
Loss of tumor suppressor adenomatous polyposis coli (APC) is thought to initiate the majority of all colorectal cancers. The predominant theory of colorectal carcinogenesis implicates stem cells as the initiating cells. However, relatively little is known about the function of APC in governing the h...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037606/ https://ncbi.nlm.nih.gov/pubmed/21199875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.205922 |
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