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The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells

Nrf2 and TGF-β1 both affect tumorigenesis in a dual fashion, either by preventing carcinogen induced carcinogenesis and suppressing tumor growth, respectively, or by conferring cytoprotection and invasiveness to tumor cells during malignant transformation. Given the involvement of Nrf2 and TGF-β1 in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Arfmann-Knübel, Sarah, Struck, Birte, Genrich, Geeske, Helm, Ole, Sipos, Bence, Sebens, Susanne, Schäfer, Heiner
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520686/
https://ncbi.nlm.nih.gov/pubmed/26226105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132978
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