The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells

Nrf2 and TGF-β1 both affect tumorigenesis in a dual fashion, either by preventing carcinogen induced carcinogenesis and suppressing tumor growth, respectively, or by conferring cytoprotection and invasiveness to tumor cells during malignant transformation. Given the involvement of Nrf2 and TGF-β1 in...

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Publicado en:PLoS One
Autores principales: Arfmann-Knübel, Sarah, Struck, Birte, Genrich, Geeske, Helm, Ole, Sipos, Bence, Sebens, Susanne, Schäfer, Heiner
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520686/
https://ncbi.nlm.nih.gov/pubmed/26226105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132978
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