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Cytoprotection “gone astray”: Nrf2 and its role in cancer

Nrf2 has gained great attention with respect to its pivotal role in cell and tissue protection. Primarily defending cells against metabolic, xenobiotic and oxidative stress, Nrf2 is essential for maintaining tissue integrity. Owing to these functions, Nrf2 is regarded as a promising drug target in t...

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Detalhes bibliográficos
Main Authors: Geismann, Claudia, Arlt, Alexander, Sebens, Susanne, Schäfer, Heiner
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155833/
https://ncbi.nlm.nih.gov/pubmed/25210464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36624
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